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Filtered Search Results
Medchemexpress LLC 4-[(3-chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile | 871307-18-5 | 99.4% | 404.83 g/mol | C21H14ClFN6 | 100MG
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Tpl2 Kinase Inhibitor 1 is a selective small-molecule inhibitor of Tpl2 (MAP3K8) used for biochemical and cell-based research. It demonstrates potent biochemical inhibition and documented cellular effects, and is supplied as a solid with defined purity and storage conditions for laboratory use.
- Biochemical IC50 ≈ 50 nM for Tpl2 (MAP3K8).
- Molecular weight 404.83 g/mol.
- Chemical formula C21H14ClFN6.
- Purity 99.4% (reported by manufacturer).
- Appearance solid, yellow to green.
- Available in solid sizes up to 100 mg.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Documented cellular activity: <5 μM (A-431 cells) and 1.1 μM (monocytes).
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Medchemexpress LLC DTPA anhydride | 23911-26-4 | ≥97.0% | 357.32 | 5 G
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DTPA anhydride is a bifunctional chelator. Its anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. It can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs), which have the ability to specifically target biomolecules and can be used in medical imaging or therapy.
- Bifunctional chelator
- Anhydride reacts with amino groups in proteins to form stable amide bonds
- Binds to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs)
- RDCs specifically target biomolecules
- Can be used in medical imaging or therapy
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Electron Microscopy Sciences Sodium Thiosulfate 5% Aqueous 500 ML
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Used in Methenamine Silver Methodfor Argentaffin Cells for staining of argentaffin granules of enterochromaffin cells. See Clark, G.: Staining Procedures, Williams and Wilkins Co., Baltimore, 3rd Ed., c. 1973, p. 161, Gomori, G., Arch. Path., 45:48, 1948 or Burtner, H.J. and Lillie, R.D., Stain Techn., 24:225-7, 1949.
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Apexbio Technology LLC LDN-212854 1432597-26-6 10mM (in 1mL DMSO)
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LDN-212854 (CAS 1432597-26-6) is a highly selective inhibitor of the bone morphogenetic protein (BMP) signaling pathway targeting ALK2 with an IC50 of 1 2 nM In kinase assays LDN-212854 demonstrates potent inhibition of constitutively active ALK2 (caALK2 IC50 16 nM) and displays substantially reduced activity against caALK5 (IC50 2 M) indicative of its BMP pathway selectivity over TGF- signaling Compared to caALK1 and caALK3 its inhibitory activity against caALK2 is 6- and 10-fold greater respectively In BMP receptor-transfected C2C12 cell models LDN-212854 preferentially inhibits caALK2-mediated signaling In transgenic models of heterotopic ossification treatment with LDN-212854 reduces ectopic bone formation This compound is a valuable tool for dissecting BMP/ALK2-driven signaling in cellular and in vivo studies
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Medchemexpress LLC Bz-DTPA | 102650-30-6 | 96.1% | 540.54 g/mol | C22H28N4O10S | 10 MG
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Bz-DTPA is a bifunctional chelator used to conjugate metal radioisotopes to biomolecules such as monoclonal antibodies. It is commonly employed in research to prepare immunoconjugates for indium-111 labeling. The product is supplied as a solid and is also available as a DMSO solution for convenience.
- Bifunctional chelator suitable for radiolabeling biomolecules.
- Used to prepare immunoconjugates for indium-111 labeling.
- Reported purity approximately 96.05%.
- Available as solid and as a 10 mM solution in DMSO.
- Available in small pack sizes (e.g., 10 mg) for research workflows.
- Store solid at 4°C protected from light; store solutions at -80°C or -20°C per guidance.
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Alkali Scientific Amoxicillin Trihydrate, 50 G
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Amoxicillin Trihydrate is a widely used beta lactam antibiotic that inhibits bacterial cell wall synthesis, making it effective against a broad spectrum of bacterial species. It is commonly utilized in microbiology research for studying bacterial growth inhibition and antibiotic susceptibility. The compound is frequently applied in laboratory settings to control bacterial contamination and to investigate resistance mechanisms. Its well established mode of action makes it suitable for experimental studies in pharmacology and microbiology. Amoxicillin is also used in cell culture environments where maintaining sterile conditions is essential for reliable experimental outcomes.
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Aqua Solutions Formaldehyde 10% w/w pH 8.5 ± 0.10 Solution (20L)
Formaldehyde 10% w/w pH 8.5 ± 0.10 Solution (20L)
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Medchemexpress LLC Bromodomain inhibitor-8 | 98.0% | 1 MG
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Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor used for treating autoimmune and inflammatory diseases.
- Acts as a BET bromodomain inhibitor
- Used for treating autoimmune diseases
- Used for treating inflammatory diseases
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Supply Solutions Avantor Performance Materials - Hydrogen Peroxide, Solution. Size: 20L; Grade: Ar (Acs); Assay: 29-32.0%.
Avantor Performance Materials - Hydrogen Peroxide, Solution. Size: 20L; Grade: AR (ACS); Assay: 29-32.0%.; Size: 20L; Grade: AR (ACS); Concentration: 29-32.0%; CAS: 7722-81-1; Hazardous: Y; Container Material: PE Drum; Formula: H?O?; Formula Weight: 34.01
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Andwin Scientific EDTA, 0.0575 Molar, 3.8 L
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EDTA, 0.0575 Molar, 3.8 L
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Pickering Laboratories Inc Artificial Saliva, Fusayama/Mayer, Custom pH, Not Stabilized, each (200 mL/bottle)
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This ready-to-use solution closely resembles themineral composition of natural saliva and can be usedfor testing a wide variety of products, including dentalmetal alloys. This formulation is at pH 4.9 and shouldbe stored refrigerated.
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Sigma Aldrich Fine Chemicals Biosciences Clobetasone butyrate British Pharmacopoeia (BP) Reference Standard | 25122-57-0 | MFCD00133196 |
Clobetasone butyrate British Pharmacopoeia (BP) Reference Standard | Mol Wt: 478.98 | 25122-57-0 | MFCD00133196 |
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Perkin Elmer US LLC BOLT PROBE
BOLT PROBE
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Selleck Chemical LLC LDN-212854
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LDN-212854 (BMP Inhibitor III) is a potent and selective BMP receptor inhibitor with IC50 of 1 3 nM for ALK2 about 2- 66- 1641- and 7135-fold selectivity over ALK1 ALK3 ALK4 and ALK5 respectively
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Electron Microscopy Sciences Sodium Bisulfite 0.05m Sol 500 ML
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For General tissue stain. References: Clark, G.: Staining Procedures, Williams & Wilkins Co., Baltimore, 3rd Ed., c. 1973, p.156.
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